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Company Name Symbol Price Prev. Close Volume % Change Change
Booking Holdings Inc. - Common Stock  BKNG 5,393.48 5492.11 48,081
-1.80%
-98.63
Alnylam Pharmaceuticals, Inc. - Common Stock  ALNY 358.57 398.29 1,823,369
-9.97%
-39.72
Equinix, Inc. - Common Stock  EQIX 765.78 800.35 621,850
-4.32%
-34.57
Fair Isaac Corporation Common Stock  FICO 1,637.12 1665.53 69,344
-1.71%
-28.41
MercadoLibre, Inc. - Common Stock  MELI 2,150.04 2178.41 189,700
-1.30%
-28.37
GeneDx Holdings Corp. - Class A Common Stock  WGS 115.51 135.38 1,044,377
-14.68%
-19.87
Abercrombie & Fitch Company Common Stock  ANF 105.58 124.87 4,001,919
-15.45%
-19.29
American Express  AXP 358.83 375.61 3,529,955
-4.47%
-16.78
Intuitive Surgical  ISRG 569.87 586.24 610,245
-2.79%
-16.37
Lumentum Holdings Inc. - Common Stock  LITE 335.29 351.42 3,446,148
-4.59%
-16.13
Praxis Precision Medicines, Inc. - Common Stock  PRAX 272.60 288.45 280,291
-5.49%
-15.85
Winmark Corporation - Common Stock  WINA 413.02 427.97 106,033
-3.49%
-14.95
Regeneron Pharmaceuticals  REGN 782.02 796.55 336,533
-1.82%
-14.53
Credit Acceptance Corporation - Common Stock  CACC 462.13 476.32 104,157
-2.98%
-14.19
Markel Group Inc. Common Stock  MKL 2,119.00 2132.84 14,015
-0.65%
-13.84
Duolingo, Inc. - Class A Common Stock  DUOL 163.86 176.66 2,376,178
-7.25%
-12.80
Royal Caribbean Cruises Ltd. Common Stock  RCL 301.14 311.50 512,980
-3.33%
-10.36
MasterCard  MA 565.20 575.54 1,752,933
-1.80%
-10.34
Ralph Lauren Corp  RL 360.00 369.81 158,850
-2.65%
-9.81
Insmed Incorporated - Common Stock  INSM 166.53 175.97 1,393,824
-5.36%
-9.44
Stryker Corp  SYK 358.54 367.54 534,287
-2.45%
-9.00
Bread Financial Holdings, Inc. Common Stock  BFH 71.84 80.36 1,316,107
-10.60%
-8.52
Insulet Corporation - Common Stock  PODD 280.54 289.04 219,031
-2.94%
-8.50
Belite Bio, Inc - American Depositary Shares  BLTE 150.00 158.36 106,990
-5.28%
-8.36
HealthEquity, Inc. - Common Stock  HQY 86.13 94.15 1,037,421
-8.52%
-8.02
Synchrony Financial Common Stock  SYF 79.60 86.89 5,449,241
-8.39%
-7.29
Atara Biotherapeutics, Inc. - Common Stock  ATRA 6.400 13.67 3,413,313
-53.18%
-7.27
First Citizens BancShares, Inc. - Class A Common Stock  FCNCA 2,167.97 2175.19 19,802
-0.33%
-7.22
UFP Technologies, Inc. - Common Stock  UFPT 250.32 257.51 133,405
-2.79%
-7.19
Thermo Fisher Scientific  TMO 611.85 618.86 1,344,800
-1.13%
-7.01
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