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Bruce Ross, Chairman
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James Mullen, Chief Executive Officer |
YOUR VOTE IS EXTREMELY IMPORTANT VOTEThE WhITE PROXY CARd FOR DIRECTORS COMMITTED TO DELIVERING SHAREHOLDER VALUE! |
FORWARd LOOkINgANd PROXY SOLICITATION TATEMENTS This presentation includes forward-looking statements about: our 2009 guidance and our financial and operational goals through the anticipated development and timing of programs in our clinical pipeline the sales potential of TYSABRI R Each forward-looking statement is subject to risks and uncertainties that could cause our continued dependence on our two principal R and RITUXAN R, the uncertainty of success in commercializing products, AVONEX R, the occurrence of adverse safety events with our products, competitive pressures, changes collaborations over which we may not always have full control, failure to execute our with our manufacturing processes and our reliance on third parties, the impact of the portfolio of marketable securities, our significant investment in a manufacturing facility-nel, the risks of doing business internationally, the actions of activist shareholders, rights and the cost of doing so, product liability claims, fluctuations in our effective governance and collaborations and the other risks and uncertainties that are described reports we file with the Securities and Exchange Commission (SEC) These forward-looking statements speak only as of the date of this presentation, and we statements, whether as a result of new information, future events, or otherwise. On April 27, 2009, Biogen Idec filed a definitive proxy statement with the SEC in are strongly advised to read the definitive proxy statement carefully before making any important information. The Companys proxy statement and any other materials filed by the at www.sec.gov or from Biogen Idec at http://investor.biogenidec.com. The Companys by writing to Biogen Idec Inc., 14 Cambridge Center, Cambridge, MA 02142 or by contacting at (877) 750-5836. |
DELIVERINGONOUR COMMITMENT TO ShAREhOLdERS Consistently delivered strong EPS and FINANCIAL 2008 results exceeded guidance PERFORMANCE Solid growth projected for 2009; Q1 revenues Continuing to grow TYSABRI and effectively OPERATIONAL Viewed as having one of the most robust PERFORMANCE Progress in pipeline; 8 programs expected in Sustained R&D investment and operationalefficiency Added two new directors after soliciting Adopting majority voting for uncontested CORPORATE Terminated the poison pill (shareholder gOVERNANCE Unilaterally waived standstill agreements $3 billion share repurchase 56M shares Maintained active dialogue with leading ACCOUNTAbILITYTO Enabled dialogue between shareholders and ShAREhOLdERS Actively engaged in soliciting shareholder |
CONSISTENTLY TRONg S TRACk ECORD DElIVEREDONThE BIOgEN IDEC ERgERgOAlS M REVENUE EPS FREE CASh FLOW ( $Billions) ($) ($ Millions) +7% 4.___+5% 3.66 +37% _,89 CAGR CAGR CAGR 3.2 2.74 2.7 2.25 737 2.2 2.4 1.9 571 643 1.40 1.57 1.22 367 03 04 05 06 07 08 03 04 05 06 07 08 04 05 06 07 08 Note: 2003 amounts represent pro forma information of the historical results of IDEC January 1, 2003. EPS numbers are diluted Non-GAAP, which excludes the impact of purchase related tax effects. Reconciliation of GAAP to non-GAAP diluted EPS and free cash flow amounts provided by operating activities less purchase of property, plant and equipment as disclosed k. |
PROdUCT REVENUES ($ in millions)+4% _,03 CAGR 1,707 1,868 AVONEX 1,417 1,543 1,169 Leading MS Therapy 03 04 05 06 07 08 ($ in millions) +8% _,8 CAGR 926 811 RITUXAN 709 616 Standard of Care for NHL 493 03 04 05 06 07 08 ($ in millions) +305% 589 CAGR TYSAbRI Powerful Efficacy 230 36 06 07 08 Note: 2003 amounts represent pro forma information of the historical results of IDEC January 1, 2003. |
bROAdAND dEEP PIPELINEMOODYS INVESTORS SERVICE ESEARCH RATES BIOGEN IDEC ThE LEAdERIN LATE-STAgE IPELINE NEUROLOgY ONCOLOgY Pre-Clinical Phase___Phase___Phase 3 Market Pre-Clinical Phase_ Phase___Phase 3 Market AVONEX R MULTIPLESCLEROSIS RITUXAN R NhL & CLL COMPLETE) (Ph 3 TYSAbRI R MULTIPLESCLEROSIS galiximab NhL bg-___MULTIPLESCLEROSIS Lumiliximab CLL daclizumab MULTIPLESCLEROSIS Volociximab SOLIdTUMORS Ocrelizumab MULTIPLESCLEROSIS hSP90 Inhibitors SOLIdTUMORS CdP33 MULTIPLESCLEROSIS gA0___NhL & CLL bIIb04 PARkINSONS TYSAbRI R MULTIPLE YELOMA PEgylated-IFN ___a MULTIPLESCLEROSIS Anti-IgF-_R SOLId Neublastin PAIN Anti-Cripto-dM4 SOLId LINgO MS RAF Inhibitor SOLId S_P___MS Anti-Fn4 SOLId bART Ad IMMUNOLOgY CARdIOPULMONARY &MERgINg REAS Pre-Clinical Phase___Phase___Phase 3 Market Pre-Clinical Phase___Phase_ Phase 3 Market RITUXAN R RhEUMATOIdARThRITIS Lixivaptan hEART FAILURE /hYPONATREMIA FUMAdERM PSORIASIS AdENTRI (IV) ACUTEhEART FAILURE TYSAbRI R CROhNS dISEASE AdENTRI (oral) ChRONIChEART FAILURE Ocrelizumab RhEUMATOIdARThRITIS Long Acting rFactor IX hEMOPhILIAb RITUXAN R ANCA-SSOCIATEd VASCULITIS Long Acting rFactor VIII hEMA AVONEX R ULCERATIVE COLITIS bg-___RhEUMATOIdARThRITIS Anti-TWEAk RA Anti-Cd40L SLE Anti-FcRn INFLAM divested discontinued Since January007 or Marketed Amevive in Psoriasis, Zevalin in NHL January 2007 Phase 2 or 3R in PPMS, RITUXANRRITUXAN in SLE, Baminercept in RA, FontolizumabR in RA Inflammatory Disorders, Phase 1 or Preclinical À in Solid Tumors, BAFF-R in LT ¿vÀ Inflammatory 6 in IPF, À Gene Delivery in Liver Mets IFN Disorders, 2007 and 2008 |
00 WEMADE SUbSTANTIALPROgRESS OVERTHEPAST GOALS YEARTOWARDACHIEVINGOUR 2010GOALS gOAL PROgRESS REVENUEgROwTh 15% top line CAGR from 2007 to+ FINANCIAL EPSgROwTh 20% bottom line CAGR from 2007 to + TYSABRI R TYSABRI patients on therapy AVONEX maintains its patient AVONEX R in the ABCR market PROdUCTS Anti-CD20 franchise growth fueled ANTI-CD20 RANChISE F in at least 2 additional indications gEOgRAPhIC MIX Over 40% of revenue from NEw PRODUCTS 2 new products or indications + PIPELINE DEVElOPMENT TATUS 6 programs in late stage + Continued execution of disciplined ACQUISITION STRATEgY external growth strategy Note: The bottom line, or EPS, reference in this slide refers to non-GAAP diluted EPS. Non-stock option expense, and other items and their related tax effects. GAAP to non-GAAP EPS |
BIOGEN IDEC BOARDOF DIRECTORS hAS OWNERSERSPECTIVE STEWARdOF ShAREhOLdER VALUE Largest merger of 2 independent biotechs $3B share repurchase/Dutch Auction Disciplined execution of business development strategy Review of strategic alternatives; including sale of the company STRONg CORPORATEgOVERNANCE Added 2 new directors after from major shareholders 5 new directors out of 13 Adopting majority voting director elections FINANCIALdISCIPLINE Terminated the poison pill Achieved 17% top-line and 25% bottom-line growth from merger through 2008 (1) 2005 reduction in force (17%) Divestiture of non-core assets Credit rating upgrade by S&P to BBB+ Cash position (2) as of March 31, 2009 of $2.5B (1)The bottom line, or EPS, reference in this slide refers to non-GAAP diluted EPS. Non-GAAP stock option expense, and other items and their related tax effects. GAAP to non-GAAP EPS (2) Includes $764 million of cash & equivalents and $1,698 million of marketable securities |
BIOGEN IDEC BOARD hASbROAdbASEd XPERIENCE CUSTOMER NObEL LAUREATE gENERAL FINANCE / NTERNATIONAL PUbLIC R&d PERSPECTIVE / / NATL CAdEMY MANAgEMENT M&A bUSINESS POLICY MARkET &ALES OF CIENCES larry Best* Alanglassberg, M.D.* Robert Pangia* Bill Young* Jim Mullen Bruce Ross Phil Sharp, Ph.D. lynn Schenk RECENT AddITIONS Cecil Pickett, Ph.D.(2006) Marijn Dekkers, Ph.D.(2007) Nancyleaming (2008) Stelios Papadopoulos, Ph.D.(2008) Brian Posner (2008) * Recommended for election to Biogen Idec board |
CONCLUSION biogen Idec has a proven track delivering exceptional performance The business is poised to create Pursuing a well-defined strategy for future Broad and deep pipeline with 8 late stage programs expected by year end 2009 Theboard is best positioned to deliver value to our shareholders Active, engaged Proactively evaluate ways to maximize Exceptional steward of value and capital Vote FOR our Nominees on theWhITE proxy card |
gAAPTONON-gAAP R ECONCILIATIONDILUTED EPS AND NET INCOME TTRIBUTABLETO BIOGEN IDEC INC. Condensed Consolidated Statements basis of Income Operating (unuadited, $ in millions, except per share amounts) FY003 FY004 FY005 FY006 FY007 FY008 GAAP diluted EPS (4.92) 0.07 0.47 0.63 1.99 2.65 Adjustment to net income attributable to Biogen Idec 6.14 1.38 1.10 Inc. (see below) 1.62 0.75 1.01 Effect of SFAS No.128 and EITF 03-06 (0.05) - - Non-gAAP diluted EPS .___.40 ___.57 ___.5 .74 _ 3.66 gAAP Net Income Attributable tobiogen Idec Inc. ($M) (875._) 5.___60.7 ___7.5 638.___783._ Revenue Pre-merger Biogen product, royalty and corporate partner 1,173.1 - revenue - COGS Fair value step up of inventory acquired from 231.6 Biogen 295.5 and Fumapharm 34.2 7.8 - COGS Pre-merger Biogen cost of sales (179.2) - - COGS Royalties related to Corixa 1.8 - - - COGS Amevive divesture - 36.4 - R&D Pre-merger Biogen net R&D (301.1) - - R&D Severance and restructuring 3.1 20.3 0.3 1.2 1.2 R&D Sale of plant - 1.9 - R&D Expenses paid by Cardiokine - - 5.2 SG&A Pre-merger Biogen SG&A (346.7) - - SG&A Merger related and purchase accounting costs - 0.1 - SG&A Severance and restructuring 13.2 9.3 19.3 2.0 0.6 3.8 Amortization of intangible assets primarily related to 33.2 Biogen merger 347.7 302.3 267.0 257.5 332.7 In-process R&D related to the Biogen Idec merger, acquisitions of Conforma, Syntonix, and Fumapharm, and consolidation of Cardiokine, Neurimmune and Escoublac and contingent consideration payment in 2008 associated with the 823.0 2006 Conforma acquisition - 330.5 84.2 25.0 Loss/(gain) on settlement of license agreements with Fumedica and Fumapharm - (6.1) - (Gain)/loss on sale of long lived assets - 111.8 (16.5) (0.4) (9.2) Other income, net: Pre-merger Biogen 32.9 - - - Other income, net: Gain on sale of long lived assets - - (7.1) Write down of investments - 12.7 - - Charitable donations and legal settlements 30.7 - - Income taxes: Income tax effect primarily related to (205.8) (195.4) reconciling (145.2) items (70.3) (65.5) (81.9) Stock option expense - 44.5 35.6 26.2 Net Income Attributable to Non-Controlling Interests: Consolidation of Cardiokine and Neurimmune and expenses paid by Cardiokine - - (65.2) (5.2) Non-gAAP Net Income Attributable tobiogen Idec Inc. 43.7 498.0 54.7 776.8 879.___,08.0 ___Free Cash Flow Reconciliation (unaudited, $ in millions) FY004 FY005 FY006 FY007 FY008 Net cash flows provided by operating activities 728.0 889.5 841.3 1,020. 1,564.5 Purchases of property, plant and equipment (Capital Expenditures) 361.0 318.4 198.3 284.1 276.0 Free Cash Flow 367.0 571.1 643.0 736.5 1,288.5 Notes: The non-GAAP financial measures presented in this table are utilized by Biogen Idec management to GAAP financial measures are defined as reported, or GAAP, values excluding (1) change relating to the initial adoption of SFAS No. 123R and (3) other items. Our management uses these comparative financial performance of the Company from year to year and quarter to quarter. Accordingly, we a result of our disclosing these non-GAAP financial measures. Non-GAAP net income attributable to Biogen reported, or GAAP, net income attributable to Biogen Idec Inc and diluted EPS. The GAAPfigures reflect: * 2004 and beyond the combined Biogen Idec Numbers may not foot due to rounding. *2003 a full year of IDEC Pharmaceuticals and 7 weeks of the former Biogen, Inc. (for the period 11/13/03 through 12/31/03) Source: Biogen Idec Annual k filings an d earnings press Reports, 10- |
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