SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  Schedule 13G

                    Under the Securities Exchange Act of 1934

                               (Amendment No. 5)*


                   Integra LifeSciences Holdings Corporation
                                (Name of Issuer)


                          Common stock, $.01 par value
                         (Title of Class of Securities)

                                    457985208
                                 (CUSIP Number)

                                December 31, 2007
             (Date of Event Which Requires Filing of this Statement)


         Check the appropriate box to designate the rule pursuant to which this
                                 Schedule is filed:

         [ ] Rule 13d-1(b)
         [ ] Rule 13d-1(c)
         [X] Rule 13d-1(d)

         *The remainder of this cover page shall be filled out for a reporting
         person's initial filing on this form with respect to the subject class
         of securities, and for any subsequent amendment containing information
         which would alter the disclosures provided in a prior cover page.

         The information required in the remainder of this cover page shall not
         be deemed to be "filed" for the purpose of Section 18 of the Securities
         Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
         that section of the Act but shall be subject to all other provisions of
         the Act (however, see the Notes).





                                                              Page 2 of 11 Pages


---------------------
CUSIP No.   457985208                 13G
---------------------

------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON: Richard E. Caruso, Ph.D.
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY
------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        United States
-------------------------------------------- ---- -----------------------------
                 NUMBER OF                        5    SOLE VOTING POWER

                  SHARES                          78,071 shares*
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         6,633,543*
                                             ---- -----------------------------
                   EACH                      7    SOLE DISPOSITIVE POWER

                                                  78,071*
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                  WITH:
                                                  6,633,543*
-------------------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        6,711,614 shares*
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)
------ ------------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.5%*
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        IN
------- -----------------------------------------------------------------------

                  *Includes 55,000 shares of common stock that may be acquired
                  upon exercise of options as of or within 60 days of February
                  1, 2008. Dr. Caruso disclaims beneficial ownership of the
                  shares owned by Tru St Partnership LP, Provco Leasing
                  Corporation and The Uncommon Individual Foundation as
                  described in this Schedule 13G (Amendment No. 5) except to the
                  extent of his pecuniary interest therein.


                                                              Page 3 of 11 Pages



---------------------
CUSIP No.   457985208                  13G
---------------------

------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON:  Tru St Partnership LP
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY
------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        Pennsylvania
-------------------------------------------- ---- -----------------------------
                 NUMBER OF                   5    SOLE VOTING POWER

                  SHARES                          0
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         6,591,205 shares
                                             ---- -----------------------------
                   EACH                      7    SOLE DISPOSITIVE POWER

                                                  0
             REPORTING PERSON                 ---- ----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  6,591,205 shares
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        6,591,205 shares
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)

------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.0%
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        PN
------- -----------------------------------------------------------------------




                                                              Page 4 of 11 Pages



---------------------
CUSIP No.   457985208                             13G
---------------------

------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON:  Provco Leasing Corporation
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY
------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        Delaware
-------------------------------------------- ---- -----------------------------
                 NUMBER OF                   5    SOLE VOTING POWER

                  SHARES                          0
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         6,614,543 shares
                                             ---- -----------------------------
                   EACH                      7    SOLE DISPOSITIVE POWER

                                                  0
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  6,614,543 shares
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        6,614,543 shares
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)

------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        25.1%
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        CO
------- -----------------------------------------------------------------------




                                                              Page 5 of 11 Pages



---------------------
CUSIP No.   457985208                             13G
---------------------

------- -----------------------------------------------------------------------
1       NAME OF REPORTING PERSON:  The Uncommon Individual Foundation
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (entities only):
------- -----------------------------------------------------------------------
2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
        (a) |X|
        (b) |_|
------- -----------------------------------------------------------------------
3       SEC USE ONLY
------- -----------------------------------------------------------------------
4       CITIZENSHIP OR PLACE OF ORGANIZATION

        Pennsylvania
-------------------------------------------- ---- -----------------------------
                 NUMBER OF                   5    SOLE VOTING POWER

                  SHARES                          0
                                             ---- -----------------------------
               BENEFICIALLY                  6    SHARED VOTING POWER

                 OWNED BY                         19,000 shares
                                             ---- -----------------------------
                   EACH                      7    SOLE DISPOSITIVE POWER

                                                  0
             REPORTING PERSON                ---- -----------------------------
                                             8    SHARED DISPOSITIVE POWER
                   WITH:
                                                  19,000 shares
------- -----------------------------------------------------------------------
9       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        19,000 shares
------- -----------------------------------------------------------------------
10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
         (See Instructions)
------- -----------------------------------------------------------------------
11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        0.072%
------- -----------------------------------------------------------------------
12      TYPE OF REPORTING PERSON (See Instructions)

        CO
------- -----------------------------------------------------------------------




                                                              Page 6 of 11 Pages


Item 1.

         (a)      Name of Issuer:  Integra LifeSciences Holdings Corporation

         (b)      Address of Issuer's Principal Executive Offices: 311
                  Enterprise Drive, Plainsboro, New Jersey  08536

Item 2.

         (a) Name of Person Filing: See (c) below.

         (b) Address of Principal Business Office or, if none, Residence: See
             (c) below.

         (c) Citizenship:

                  Richard E. Caruso Ph.D.
                  795 East Lancaster Ave., Suite 200
                  Villanova, Pennsylvania  19085
                  United States citizen

                  Tru St Partnership LP
                  795 East Lancaster Ave., Suite 200
                  Villanova, Pennsylvania  19085
                  Pennsylvania limited partnership

                  Provco Leasing Corporation
                  209B Baynard Building
                  3411 Silverside Road
                  Wilmington, Delaware  19810
                  Delaware corporation

                  The Uncommon Individual Foundation
                  795 East Lancaster Ave., Suite 204
                  Villanova, Pennsylvania  19085
                  Pennsylvania corporation

         (d) Title of Class of Securities: common stock, $.01 par value.

         (e) CUSIP Number: 457985208

Item 3.           Not applicable.

Item 4.           Ownership: Provide the following information regarding the
                  aggregate number and percentage of the class of securities of
                  the issuer identified in Item 1.

          (a)         Amount beneficially owned:  As of December 31, 2007, Dr.
                      Caruso may be deemed the beneficial owner of 6,711,614
                      shares of common stock.  He individually holds 23,071
                      shares and holds options to purchase 55,000 shares of
                      common stock that are exercisable within 60 days of
                      February 1, 2008.  Tru St Partnership LP ("Tru St") may be
                      deemed the beneficial owner of 6,591,205 shares of common
                      stock.  Dr. Caruso is the president and sole director of
                      Provco Leasing Corporation ("Provco Leasing").  Provco


                                                              Page 7 of 11 Pages


                      Leasing is the corporate general partner of Tru St.
                      Provco Leasing is also the beneficial owner of 23,338
                      shares of common stock.  The Uncommon Individual
                      Foundation is the beneficial owner of 19,000 shares of
                      common stock.  Dr. Caruso is the founder and chief
                      executive officer of The Uncommon Individual Foundation.
                      Dr. Caruso disclaims beneficial ownership of shares held
                      by Tru St, Provco Leasing and The Uncommon Individual
                      Foundation except to the extent of his pecuniary interest
                      therein.

                  (b) Percent of Class: Based on 26,363,053 shares of the
                      Issuer's common stock outstanding as of November 5, 2007
                      as reported in the Issuer's Form 10-Q for the quarter
                      ended September 20, 2007: Dr. Caruso may be deemed the
                      beneficial owner of 25.5% of the Issuer's common stock;
                      Tru St, may be deemed the beneficial owner of 25.0% of the
                      Issuer's common stock; Provco Leasing may be deemed the
                      beneficial owner of 25.1% of the Issuer's common stock and
                      The Uncommon Individual Foundation may be deemed the
                      beneficial owner of 0.072% of the Issuer's common stock.

                  (c) The Reporting Persons have the power to vote or dispose of
                      the number of shares as follows:

                           (i)      Sole power to vote or direct the vote. Dr.
                                    Caruso may be deemed to have sole power to
                                    vote or direct the vote of 78,071 shares of
                                    common stock based on his ownership of
                                    23,071 shares and options to purchase 55,000
                                    shares of common stock that are exercisable
                                    within 60 days of February 1, 2008.

                           (ii)     Shared power to vote or direct the vote. Dr.
                                    Caruso, Tru St, Provco Leasing and The
                                    Uncommon Individual Foundation may be deemed
                                    to share the power to vote or direct the
                                    vote with respect to 6,633,543 shares of
                                    common stock. Dr. Caruso and Tru St may be
                                    deemed to share the power to vote or direct
                                    the vote with respect to 6,591,205 shares of
                                    common stock. Dr. Caruso and Provco Leasing
                                    may be deemed to share the power to vote or
                                    direct the vote with respect to 6,614,543
                                    shares of common stock. Dr. Caruso and The
                                    Uncommon Individual Foundation may be deemed
                                    to share the power to vote or direct the
                                    vote with respect to 19,000 shares of common
                                    stock.

                           (iii)    Sole power to dispose or direct the
                                    disposition. Dr. Caruso has sole power to
                                    dispose or control the disposition of 78,071
                                    shares of common stock based on his
                                    ownership of 23,071 shares and options to
                                    purchase 55,000 shares of common stock that
                                    are exercisable within 60 days of February
                                    1, 2008.

                           (iv)     Shared power to dispose or direct the
                                    disposition.  Dr. Caruso, Tru St Provco
                                    Leasing and The Uncommon Individual
                                    Foundation may be deemed to have shared
                                    power to dispose of or shared power to
                                    direct the disposition of 6,633,543 shares
                                    of common stock. Dr. Caruso and Tru St may
                                    be deemed to have shared power to dispose of
                                    or shared power to direct the disposition of
                                    6,591,205 shares of common stock.  Dr.
                                    Caruso and Provco Leasing may be deemed to
                                    have shared power to dispose of or shared
                                    power to direct the disposition of 6,614,543
                                    shares of common stock.  Dr. Caruso and The
                                    Uncommon Individual Foundation may be deemed
                                    to have shared power to dispose of or direct
                                    the disposition of 19,000 shares of common
                                    stock.

                                                              Page 8 of 11 Pages


Item 5.           Ownership of Five Percent or less of a Class:

                  Not applicable.

Item 6.           Ownership of More Than Five Percent on Behalf of Another
                  Person:

                  Not applicable

Item 7.           Identification and Classification of the Subsidiary which
                  Acquired the Security Reported on by the Parent Holding
                  Company:

                  Not applicable

Item 8.           Identification and Classification of Members of the Group:

                  Exhibit A attached hereto identifies each member of the group
                  filing this Schedule 13G/A pursuant to Rule 13d-1(c).

Item 9.           Notice of Dissolution of Group:
                  Not applicable

Item 10. Certification:  Not applicable.


                                    Signature

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.


Date:    February 5, 2008                  /s/ Richard E. Caruso, Ph.D.
                                            ------------------------------
                                               Richard E. Caruso, Ph.D.


TRU ST PARTNERSHIP LP
PROVCO LEASING CORPORATION, GP

By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its: President


PROVCO LEASING CORPORATION


By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its: President


THE UNCOMMON INDIVIDUAL FOUNDATION


By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its: President




                                                              Page 9 of 11 Pages


                                  Exhibit Index

Exhibit                           Title                              Page No.

Exhibit A                         Group Members                        12

Exhibit B                         Joint Filing Agreement               13



                                                             Page 10 of 11 Pages


                                    EXHIBIT A


                                  Group Members


                            Richard E. Caruso, Ph.D.
                              Tru St Partnership LP
                           Provco Leasing Corporation
                       The Uncommon Individual Foundation



                                                             Page 11 of 11 Pages


                                    EXHIBIT B

                             Joint Filing Agreement

         In accordance with Rule 13d-1(k) under the Securities Exchange Act of
1934, as amended, the persons named below agree to the joint filing on behalf of
each of them of a Statement on Schedule 13G/A (including amendments thereto)
with respect to the common stock, par value $.01 per share of Integra
LifeSciences Holdings Corporation, and further agree that this Joint Filing
Agreement be included as Exhibit to such joint filings. In evidence thereof, the
undersigned, being duly authorized, have executed this Joint Filing Agreement
this fifth day of February 2008.


TRU ST PARTNERSHIP LP
PROVOCO LEASING CORPORATION, GP

By: /s/ Richard E. Caruos, Ph.D.           By: /s/ Richard E. Caruso, Ph.D.
    ------------------------                   ----------------------------
Its: President                                     Richard E. Caruso, Ph.D.


PROVCO LEASING CORPORATION


By: /s/ Richard E. Caruso, Ph.D.
    ------------------------
Its: President


THE UNCOMMON INDIVIDUAL FOUNDATION


By: /s/ Richard E. Caruso, Ph.D.
    ----------------------------
Its: President