Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
TPG Group Holdings (SBS) Advisors, Inc.
  2. Issuer Name and Ticker or Trading Symbol
MACROGENICS INC [MGNX]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
_____ Officer (give title below) __X__ Other (specify below)
Former 10% Owner
(Last)
(First)
(Middle)
C/O TPG GLOBAL, LLC, 301 COMMERCE STREET, SUITE 3300
3. Date of Earliest Transaction (Month/Day/Year)
10/16/2013
(Street)

FORT WORTH, TX 76102
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/16/2013   C   2,208,762 A (4) (5) 2,208,762 I See Explanation of Responses (1) (2) (6) (7)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants to purchase Series D-2 Convertible Preferred Stock (3) 10/16/2013   C     28,753   (3)   (3) Series D-2 Convertible Preferred Stock 28,753 (3) 0 I See Explanation of Responses (1) (2) (6) (7)
Series D-2 Convertible Preferred Stock (4) (5) 10/16/2013   C   28,753     (4)(5)   (4)(5) Common Stock 1,530 (3) (4) (5) 412,129 I See Explanation of Responses (1) (2) (6) (7)
Series D-2 Convertible Preferred Stock (4) (5) 10/16/2013   J(3)     22,002   (4)(5)   (4)(5) Common Stock 1,172 (3) (4) (5) 390,127 I See Explanation of Responses (1) (2) (6) (7)
Series B-1 Convertible Preferred Stock (4) (5) 10/16/2013   C     18,728,346   (4)(5)   (4)(5) Common Stock 1,137,333 (4) (5) 0 I See Explanation of Responses (1) (2) (6) (7)
Series C Convertible Preferred Stock (4) (5) 10/16/2013   C     19,724,839   (4)(5)   (4)(5) Common Stock 1,050,651 (4) (5) 0 I See Explanation of Responses (1) (2) (6) (7)
Series D-2 Convertible Preferred Stock (4) (5) 10/16/2013   C     390,127   (4)(5)   (4)(5) Common Stock 20,778 (4) (5) 0 I See Explanation of Responses (1) (2) (6) (7)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
TPG Group Holdings (SBS) Advisors, Inc.
C/O TPG GLOBAL, LLC
301 COMMERCE STREET, SUITE 3300
FORT WORTH, TX 76102
      Former 10% Owner
BONDERMAN DAVID
C/O TPG GLOBAL, LLC
301 COMMERCE STREET, SUITE 3300
FORT WORTH, TX 76102
      Former 10% Owner
COULTER JAMES G
C/O TPG GLOBAL, LLC
301 COMMERCE STREET, SUITE 3300
FORT WORTH, TX 76102
      Former 10% Owner

Signatures

 /s/ Ronald Cami, Vice President, TPG Group Holdings (SBS) Advisors, Inc. (8)   10/18/2013
**Signature of Reporting Person Date

 /s/ Ronald Cami, on behalf of David Bonderman (8) (9)   10/18/2013
**Signature of Reporting Person Date

 /s/ Ronald Cami, on behalf of James G. Coulter (8) (9)   10/18/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) David Bonderman and James G. Coulter are officers and sole shareholders of TPG Group Holdings (SBS) Advisors, Inc. ("Group Advisors" and, together with Messrs. Bonderman and Coulter, the "Reporting Persons"), which is the general partner of TPG Group Holdings (SBS), L.P., which is the sole member of TPG Holdings I-A, LLC, which is the general partner of TPG Holdings I, L.P., which is the sole member of each of TPG Biotechnology GenPar Advisors, LLC ("TPG Biotech GenPar Advisors") and TPG Ventures GenPar Advisors, LLC ("TPG Ventures GenPar Advisors").
(2) TPG Biotech GenPar Advisors is the general partner of TPG Biotechnology GenPar, L.P., which is the general partner of TPG Biotechnology Partners, L.P. ("TPG Biotech"), which directly holds 1,877,449 shares of Common Stock ("Common Stock") of MacroGenics, Inc. (the "Issuer"). TPG Ventures GenPar Advisors is the general partner of TPG Ventures GenPar, L.P., which is the general partner of TPG Ventures, L.P. ("TPG Ventures" and, together with TPG Biotech, the "TPG Funds"), which directly holds 331,313 shares of Common Stock.
(3) On October 16, 2013, the TPG Funds exercised warrants (the "Warrants") to purchase an aggregate of 28,753 shares of Series D-2 Convertible Preferred Stock ("Series D-2 Preferred") of the Issuer at an exercise price of $0.6521 per share of Series D-2 Preferred. In lieu of paying the exercise price per share in cash, the TPG Funds elected to receive a number of shares of Series D-2 Preferred net of the number of shares of Series D-2 Preferred whose fair market value equaled the aggregate exercise price. The Warrants had been exercisable by the holder at any time on or after September 24, 2008 until September 24, 2018, subject to certain early termination events.
(4) On October 16, 2013, (a) the shares of Series B-1 Convertible Preferred Stock of the Issuer (the "Series B Preferred") held by the TPG Funds mandatorily converted into 1,137,333 shares of Common Stock, (b) the shares of Series C Convertible Preferred Stock of the Issuer (the "Series C Preferred") held by the TPG Funds mandatorily converted into 1,050,651 shares of Common Stock and (c) the shares of Series D-2 Preferred mandatorily converted into 20,778 shares of Common Stock. Pursuant to the Amended and Restated Certificate of Incorporation of the Issuer, as amended, the shares of Series B Preferred, Series C Preferred and Series D-2 Preferred had been convertible, at the option of the holder, at any time into shares of Common Stock at initial conversion rates equal to (a) 1.1401 shares of Common Stock per share of Series B Preferred, (b) one share of Common Stock per share of Series C Preferred and (c) one share of Common Stock per share of Series D-2 Preferred.
(5) The initial conversion rates were adjusted as a result of a 1-for-18.7739 reverse stock split of the Common Stock. Pursuant to the Amended and Restated Certificate of Incorporation of the Issuer, as amended, the shares of Series B Preferred, Series C Preferred and Series D-2 Preferred had been convertible, at the option of the holder, at any time into shares of Common Stock at initial conversion rates equal to (a) 1.1401 shares of Common Stock per share of Series B Preferred, (b) one share of Common Stock per share of Series C Preferred and (c) one share of Common Stock per share of Series D-2 Preferred. The initial conversion rates were adjusted as a result of a 1-for-18.7739 reverse stock split of the Common Stock.
(6) Because of the relationship between the Reporting Persons and the TPG Funds, the Reporting Persons may be deemed to beneficially own the securities reported herein to the extent of the greater of their respective direct or indirect pecuniary interests in the profits or capital accounts of the TPG Funds. Each Reporting Person and each of the TPG Funds disclaims beneficial ownership of the securities reported herein, except to the extent of such Reporting Person's or such TPG Fund's pecuniary interest therein, if any.
(7) Pursuant to Rule 16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), this filing shall not be deemed an admission that the Reporting Persons are, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owners of any equity securities in excess of their respective pecuniary interests.
 
Remarks:
(8) The Reporting Persons are jointly filing this Form 4 pursuant to Rule 16a-3(j) under the Exchange Act.

(9) Ronald Cami is signing on behalf of both Messrs. Bonderman and Coulter pursuant to authorization and designation letters dated July 1, 2013, which were previously filed with the Securities and Exchange Commission.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.