Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  DEPARLE NANCY ANN
 2. Date of Event Requiring Statement (Month/Day/Year)
04/24/2006		 3. Issuer Name and Ticker or Trading Symbol
BOSTON SCIENTIFIC CORP [(BSX)]
(Last)
(First)
(Middle)
ONE BOSTON SCIENTIFIC PLACE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NATICK, MA 017601537		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 4,871
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   (1) 05/18/2012 Common Stock 26,891 $ 10.52 D  
Stock Option (Right to Buy)   (1) 05/19/2013 Common Stock 35,855 $ 11.42 D  
Stock Option (Right to Buy)   (1) 05/18/2014 Common Stock 35,855 $ 16.46 D  
Stock Option (Right to Buy)   (1) 05/16/2015 Common Stock 26,891 $ 20.45 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
DEPARLE NANCY ANN
ONE BOSTON SCIENTIFIC PLACE
NATICK, MA 017601537		   X      

Signatures

By: /s/ Lawrence J. Knopf, Attorney-in-fact 05/03/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Reflects options to purchase common stock of Boston Scientific originally granted as options to purchase common stock of Guidant Corporation and assumed by Boston Scientific in connection with its acquisition of Guidant. These options are fully exercisable.

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