Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  INTERWEST PARTNERS VIII LP
2. Date of Event Requiring Statement (Month/Day/Year)
10/09/2013
3. Issuer Name and Ticker or Trading Symbol
MACROGENICS INC [MGNX]
(Last)
(First)
(Middle)
2710 SAND HILL RD, SUITE 200
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

MENLO PARK, CA 94025
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series A-1 Convertible Preferred Stock   (1)   (1) Common Stock 12,001,000 $ (1) I See Footnote (2)
Series B Convertible Preferred Stock   (3)   (3) Common Stock 10,131,856 $ (3) I See Footnote (4)
Series C Convertible Preferred Stock   (5)   (5) Common Stock 5,547,611 $ (5) I See Footnote (6)
Series D-2 Convertible Preferred Stock   (5)   (5) Common Stock 613,402 $ (5) I See Footnote (7)
Series D-2 Convertible Preferred Stock Warrants   (8)   (9) Common Stock 46,005 $ (5) I See Footnote (10)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
INTERWEST PARTNERS VIII LP
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
InterWest Management Partners VIII, LLC
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
INTERWEST INVESTORS VIII L P
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
INTERWEST INVESTORS Q VIII LP
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
CASH HARVEY B
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
GIANOS PHILIP T
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
Kliman Gilbert H
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
HEDRICK W SCOTT
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    
Holmes W Stephen
2710 SAND HILL RD
SUITE 200
MENLO PARK, CA 94025
    X    

Signatures

/s/ W. Stephen Holmes, Managing Director 10/09/2013
**Signature of Reporting Person Date

/s/ W. Stephen Holmes, Managing Director 10/09/2013
**Signature of Reporting Person Date

/s/ W. Stephen Holmes, Managing Director 10/09/2013
**Signature of Reporting Person Date

/s/ W. Stephen Holmes, Managing Director 10/09/2013
**Signature of Reporting Person Date

/s/ Harvey B. Cash by Karen A. Wilson Power of Attorney 10/09/2013
**Signature of Reporting Person Date

/s/ Philip T. Gianos by Karen A. Wilson Power of Attorney 10/09/2013
**Signature of Reporting Person Date

/s/ Gilbert H. Kliman by Karen A. Wilson Power of Attorney 10/09/2013
**Signature of Reporting Person Date

/s/ W. Scott Hedrick by Karen A. Wilson Power of Attorney 10/09/2013
**Signature of Reporting Person Date

/s/ W. Stephen Holmes By Karen A. Wilson Power of Attorney 10/09/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Each share of Series A-1 Convertible Preferred Stock is convertible into 0.0802 of a share of Common Stock without payment of further consideraton and will automatically convert into 0.0802 of a share of Common Stock upon closing of the Issuer's initial public offering without payment of futher consideration. The shares have no expiration date.
(2) These securities are held as follows: 11,575,052 by InterWest Partners VIII, LP ("IW8"), 93,748 by InterWest Investors VIII, LP ("II8") and 332,200 by InterWest Investors Q VIII, LP ("IIQ8") (collectively, the "InterWest Funds"). InterWest Management Partners VIII, LLC ("IMP8") is the General Partner of IW8, II8 and IIQ8 and has sole voting and investment control over the shares owned by IW8, II8 and IIQ8. Harvey B. Cash, Philip T. Gianos, W. Scott Hedrick, W. Stephen Holmes, Gilbert H. Kliman and Arnold L. Oronsky are Managing Directors of IMP8 and disclaim beneficial ownership of those securities, except to the extent of their pecuniary interest therein.
(3) Each share of Series B Convertible Preferred Stock is convertible into 0.0607 of a share of Common Stock without payment of further consideraton and will automatically convert into 0.0607 of a share of Common Stock upon closing of the Issuer's initial public offering without payment of futher consideration. The shares have no expiration date.
(4) These securities are held as follows: 9,774,202 by IW8, 78,015 by II8 and 279,639 by IIQ8. IMP8 is the General Partner of IW8, II8 and IIQ8 and has sole voting and investment control over the shares owned by IW8, II8 and IIQ8. Harvey B. Cash, Philip T. Gianos, W. Scott Hedrick, W. Stephen Holmes, Gilbert H. Kliman and Arnold L. Oronsky are Managing Directors of IMP8 and disclaim beneficial ownership of those securities, except to the extent of their pecuniary interest therein.
(5) Each share of Series C Convertible Preferred Stock and each share of Series D-2 Convertible Preferred Stock is convertible into 0.0533 of a share of Common Stock without payment of further consideraton and will automatically convert into 0.0533 of a share of Common Stock upon closing of the Issuer's initial public offering without payment of futher consideration. The shares have no expiration date.
(6) These securities are held as follows: 5,351,780 by IW8, 42,717 by II8 and 153,114 by IIQ8. IMP8 is the General Partner of IW8, II8 and IIQ8 and has sole voting and investment control over the shares owned by IW8, II8 and IIQ8. Harvey B. Cash, Philip T. Gianos, W. Scott Hedrick, W. Stephen Holmes, Gilbert H. Kliman and Arnold L. Oronsky are Managing Directors of IMP8 and disclaim beneficial ownership of those securities, except to the extent of their pecuniary interest therein.
(7) These securities are held as follows: 591,749 by IW8, 4,723 by II8 and 16,930 by IIQ8. IMP8 is the General Partner of IW8, II8 and IIQ8 and has sole voting and investment control over the shares owned by IW8, II8 and IIQ8. Harvey B. Cash, Philip T. Gianos, W. Scott Hedrick, W. Stephen Holmes, Gilbert H. Kliman and Arnold L. Oronsky are Managing Directors of IMP8 and disclaim beneficial ownership of those securities, except to the extent of their pecuniary interest therein.
(8) Immediately.
(9) The warrants will expire upon the closing of the initial public offering.
(10) These securities are held as follows: 44,381 by IW8, 354 by II8 and 1,270 by IIQ8. IMP8 is the General Partner of IW8, II8 and IIQ8 and has sole voting and investment control over the shares owned by IW8, II8 and IIQ8. Harvey B. Cash, Philip T. Gianos, W. Scott Hedrick, W. Stephen Holmes, Gilbert H. Kliman and Arnold L. Oronsky are Managing Directors of IMP8 and disclaim beneficial ownership of those securities, except to the extent of their pecuniary interest therein.

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