Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Khosla Ventures II, L.P.
  2. Issuer Name and Ticker or Trading Symbol
AMYRIS, INC. [AMRS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
3000 SAND HILL ROAD, BUILDING 3, SUITE 190
3. Date of Earliest Transaction (Month/Day/Year)
09/30/2010
(Street)

MENLO PARK, CA 94025
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/30/2010   C   419,687 A (1) 564,853 I See Footnote (2)
Common Stock 09/30/2010   C   3,179,674 A (3) 3,179,674 I See Footnote (4)
Common Stock 09/30/2010   C   155,311 A (5) 3,334,985 I See Footnote (4)
Common Stock 09/30/2010   C   58,472 A (3) 58,472 D (6)  
Common Stock 09/30/2010   C   2,856 A (5) 61,328 D (6)  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Convertible Preferred Stock (3) 09/30/2010   C     3,179,674   (3)   (3) Common Stock 3,179,674 $ 0 0 I See Footnote (4)
Series B Convertible Preferred Stock (5) 09/30/2010   C     138,919   (5)   (5) Common Stock 155,311 $ 0 0 I See Footnote (4)
Series C Convertible Preferred Stock (1) 09/30/2010   C     419,687   (1)   (1) Common Stock 419,687 $ 0 0 I See Footnote (2)
Series A Convertible Preferred Stock (3) 09/30/2010   C     58,472   (3)   (3) Common Stock 58,472 $ 0 0 D (6)  
Series B Convertible Preferred Stock (5) 09/30/2010   C     2,555   (5)   (5) Common Stock 2,856 $ 0 0 D (6)  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Khosla Ventures II, L.P.
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures Associates II, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures III, L.P.
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures Associates III, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
VK Services, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    

Signatures

 /s/ Khosla Ventures II, L.P., by Khosla Ventures Associates II, LLC, its General Partner   09/30/2010
**Signature of Reporting Person Date

 /s/ Khosla Ventures Associates II, LLC   09/30/2010
**Signature of Reporting Person Date

 /s/ Khosla Ventures III, L.P., by Khosla Ventures Associates III, LLC, its General Partner   09/30/2010
**Signature of Reporting Person Date

 /s/ Khosla Ventures Associates III, LLC   09/30/2010
**Signature of Reporting Person Date

 /s/ VK Services, LLC, by Vinod Khosla, its Managing Director   09/30/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Each share of the Issuer's Series C Preferred Stock converted automatically into shares of the Issuer's Common Stock on a 1 to 1 basis immediately prior to the closing of the Issuer's initial public offering and had no expiration date.
(2) The securities are owned by Khosla Ventures III, L.P. ("Khosla III"). Khosla Ventures Associates III, LLC ("KVA III") is the general partner of Khosla III and possesses sole voting and investment control over the shares owned by Khosla III and may be deemed to have indirect beneficial ownership of the shares held by Khosla III. KVA III however owns no securities of the Issuer directly. Each Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.
(3) Each share of the Issuer's Series A Preferred Stock converted automatically into shares of the Issuer's Common Stock on a 1 to 1 basis immediately prior to the closing of the Issuer's initial public offering and had no expiration date.
(4) The securities are owned by Khosla Ventures II, L.P. ("Khosla II"). VK Services, LLC serves as the manager of Khosla Ventures Associates II, LLC ("KVA II"), which serves as the general partner of Khosla II, and VK Services, LLC possesses sole voting and investment control over the shares owned by Khosla II and may be deemed to have indirect beneficial ownership of the shares held by Khosla II. KVA II however owns no securities of the Issuer directly. Each Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.
(5) Each share of the Issuer's Series B Preferred Stock converted automatically into shares of the Issuer's Common Stock on a 1 to 1.118 basis immediately prior to the closing of the Issuer's initial public offering and had no expiration date.
(6) The securities are owned by VK Services, LLC. VK Services, LLC serves as the manager of KVA II.
 
Remarks:
Exhibit List
Exhibit 99 - Joint Filer Information

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