Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Khosla Ventures II, L.P.
2. Date of Event Requiring Statement (Month/Day/Year)
09/27/2010
3. Issuer Name and Ticker or Trading Symbol
AMYRIS, INC. [AMRS]
(Last)
(First)
(Middle)
3000 SAND HILL ROAD, BUILDING 3, SUITE 190
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

MENLO PARK, CA 94025
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 145,166
I
See Footnote (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Convertible Preferred Stock   (2)   (2) Common Stock 3,179,674 (2) $ (2) I See Footnote (3)
Series B Convertible Preferred Stock   (4)   (4) Common Stock 138,919 (4) $ (4) I See Footnote (3)
Series C Convertible Preferred Stock   (2)   (2) Common Stock 419,687 (2) $ (2) I See Footnote (1)
Series A Convertible Preferred Stock   (2)   (2) Common Stock 58,472 (2) $ (2) D (5)  
Series B Convertible Preferred Stock   (4)   (4) Common Stock 2,555 (4) $ (4) D (5)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Khosla Ventures II, L.P.
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures Associates II, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures III, L.P.
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
Khosla Ventures Associates III, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    
VK Services, LLC
3000 SAND HILL ROAD
BUILDING 3, SUITE 190
MENLO PARK, CA 94025
    X    

Signatures

/s/ Khosla Ventures II, L.P., by Khosla Ventures Associates II, LLC, its General Partner 09/27/2010
**Signature of Reporting Person Date

/s/ Khosla Ventures Associates II, LLC 09/27/2010
**Signature of Reporting Person Date

/s/ Khosla Ventures III, L.P., by Khosla Ventures Associates III, LLC, its General Partner 09/27/2010
**Signature of Reporting Person Date

/s/ Khosla Ventures Associates III, LLC 09/27/2010
**Signature of Reporting Person Date

/s/ VK Services, LLC, by Vinod Khosla, its Managing Director 09/27/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The securities are owned by Khosla Ventures III, L.P. ("Khosla III"). Khosla Ventures Associates III, LLC ("KVA III") is the general partner of Khosla III and possesses sole voting and investment control over the shares owned by Khosla III and may be deemed to have indirect beneficial ownership of the shares held by Khosla III. KVA III however owns no securities of the Issuer directly. Each Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.
(2) Upon the closing of the Issuer's initial public offering, each outstanding share of Series A Preferred Stock and Series C Preferred Stock will be automatically converted into one share of the Issuer's Common Stock. The Series A Preferred Stock and Series C Preferred Stock have no expiration date.
(3) The securities are owned by Khosla Ventures II, L.P. ("Khosla II"). VK Services, LLC serves as the manager of Khosla Ventures Associates II, LLC ("KVA II"), which serves as the general partner of Khosla II, and VK Services, LLC possesses sole voting and investment control over the shares owned by Khosla II and may be deemed to have indirect beneficial ownership of the shares held by Khosla II. KVA II however owns no securities of the Issuer directly. Each Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.
(4) Upon completion of the Issuer's initial public offering, each outstanding share of Series B Preferred Stock will be automatically converted into 1.118 shares of the Issuer's Common Stock. The number of shares of underlying Common Stock reported in Column 3 does not reflect this automatic conversion. The Series B Preferred Stock has no expiration date.
(5) The securities are owned by VK Services, LLC. VK Services, LLC serves as the manager of KVA II.
 
Remarks:
Exhibit List ------------------ Exhibit 99 - Joint Filer Information Statement

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