FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Boisseau Philippe   2. Issuer Name and Ticker or Trading Symbol AMYRIS, INC. [AMRS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 24 COURS MICHELET 3. Date of Earliest Transaction (Month/Day/Year) 10/16/2013 (Street) 92800 PUTEAUX, I0  4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock               13,617,212 I By Total Energies Nouvelles Activites USA (1)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

1.5% Senior Unsecured Convertible Note Due 2017 ("Note")

$ 7.0682

10/16/2013

J(2)

$ 33,300,001.04 (2)

(2)

(2)

Common Stock

$ 33,300,001.04 (2)

$ 0

$ 0 (2)

I

By Total Energies Nouvelles Activites USA (1)

1.5% Senior Unsecured Convertible Note Due 2017 ("New Note")

$ 7.0682

10/16/2013

P

$ 24,047,816.63 (3)

(3)

(3)

Common Stock

$ 24,047,816.63 (3)

$ 0

$ 24,047,816.63 (3)

I

By Total Energies Nouvelles Activites USA (1)

Tranche I Senior Convertible Note ("Tranche Note")

$ 2.44

10/16/2013

P

$ 9,252,184.41 (4)

(4)

(4)

Common Stock

$ 9,252,184.41 (4)

$ 0

$ 9,252,184.41 (4)

I

By Total Energies Nouvelles Activites USA (1)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Boisseau Philippe 24 COURS MICHELET 92800 PUTEAUX, I0	X	X

Signatures

/s/ Philippe Boisseau by Nicholas Khadder, Attorney-in-Fact		10/18/2013
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Mr. Boisseau, a member of the Issuer's board of directors, is a member of the Executive Committee of Total S.A., the ultimate parent company of Total Energies Nouvelles Activites USA, and, as such, may be deemed to share voting or investment power over the securities held by Total Energies Nouvelles Activites USA. Mr. Boisseau holds no shares of the Issuer directly and disclaims beneficial ownership of the Common Stock, except to the extent of his pecuniary interest therein, if any.
(2)	Note was cancelled pursuant to that certain Request for Cancellation delivered by the Reporting Person and accepted by the Issuer. The Issuer's obligations under the Note were cancelled upon the issuances of a new 1.5% Senior Unsecured Convertible Note Due 2017 and new Tranche I Senior Convertible Note.
(3)	The principal amount of the New Note is $24,047,816.63. The New Note is convertible only in those circumstances described in the New Note. The Final Maturity Date as defined in the New Note is March 1, 2017.
(4)	The principal amount of the Tranche Note is $9,252,184.41. The Tranche Note is convertible only in those circumstances described in the Tranche Note. The Final Maturity Date as defined in the Tranche Note is October 16, 2018.

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