UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


                         Date of Report: April 22, 2005
                        (Date of earliest event reported)


                          21ST CENTURY HOLDING COMPANY
                          ----------------------------
             (Exact name of registrant as specified in its charter)


           Florida                        0-2500111             65-0248866
-------------------------------     ---------------------  --------------------
(State or other jurisdiction of       (Commission File        (I.R.S. Employer
         incorporation)                   Number)            Identification No.)


       3661 West Oakland Park Blvd., Suite 300
                Lauderdale Lakes, FL                              33311
------------------------------------------------------      ------------------
      (Address of principal executive offices)                 (Zip Code)


       Registrant's telephone number, including area code: (954) 581-9993

                                 NOT APPLICABLE
                          -----------------------------
          (Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_| Written communications pursuant to Rule 425 under the Securities Act (17 CFR
230.425)

|_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
240.14a-12)

|_| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
Act (17 CFR 240.14d-2(b))

|_| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
Act (17 CFR 240.13e-4(c))




Item 2.02 Results of Operations and Financial Condition.

      On April 22, 2005, 21st Century Holding Company (the "Company") issued a
press release raising its first quarter guidance from $0.70 - $0.75 per share to
$0.80 - $0.85 per share and announcing that it will release its first quarter
2005 financial results after the market closes on Wednesday, April 27, 2005
followed by an investor conference call at 4:30 PM (ET). A copy of the press
release is attached to this current report on Form 8-K as Exhibit 99.1 and
incorporated herein by reference.

The information in this Current Report on Form 8-K and Exhibit 99.1 attached
hereto is hereby intended to be furnished pursuant to Item 2.02, "Results of
Operations and Financial Condition". As provided in General Instruction B.6 of
SEC Form 8-K, such information shall not be deemed "filed" for purposes of
Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange
Act"), or otherwise subject to the liabilities of that section, and it shall not
be deemed incorporated by reference in any filing under the Securities Act of
1933, as amended, or under the Exchange Act, whether made before or after the
date hereof, except as expressly set forth by specific reference in such filing
to this Current Report on Form 8-K.

Item 9.01 Financial Statements and Exhibits.

      (a)   Exhibits.

      99.1 21st Century Holding Company Press Release, dated April 22, 2005.




                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                    21ST CENTURY HOLDING COMPANY


Date: April 25, 2005                By:   /s/   Richard A. Widdicombe
                                        -----------------------------
                                    Name:    Richard A. Widdicombe
                                    Title:   Chief Executive Officer
                                             (Principal Executive Officer)

Date: April 25, 2005                By:   /s/   James Gordon Jennings, III
                                        ----------------------------------
                                    Name:    James Gordon Jennings, III
                                    Title:   Chief Financial Officer
                                    (Principal Accounting and Financial Officer)




                                  EXHIBIT INDEX
                                  -------------


Exhibit No.    Exhibit Title
-----------    -------------
      99.1     21st Century Holding Company Press Release, dated April 22, 2005.