Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
YOWELL JOHN B
  2. Issuer Name and Ticker or Trading Symbol
OLD DOMINION FREIGHT LINE INC/VA [ODFL]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
__X__ Officer (give title below) __X__ Other (specify below)
Executive VP and COO / Member of Section 13(d) group
(Last)
(First)
(Middle)
C/O OLD DOMINION FREIGHT LINE, INC., 500 OLD DOMINION WAY
3. Date of Earliest Transaction (Month/Day/Year)
09/15/2010
(Street)

THOMASVILLE, NC 27360
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/15/2010   S(1)   966 D $ 25.3404 (2) 146,529 I As co-trustee of the Seth Morgan Yowell Irrevocable Declaration of Trust
Common Stock 09/15/2010   S(1)   966 D $ 25.3404 (2) 146,529 I As co-trustee of the Megan Elise Yowell Irrevocable Declaration of Trust
Common Stock 09/15/2010   S(1)   50 D $ 25.3404 (2) 46,663 I By Audrey L. Congdon Irrevocable Trust No. 2 dated 5/28/04 (David Congdon, Trustee)
Common Stock 09/15/2010   S(1)   1,962 D $ 25.3404 (2) 829,827 I By wife as trustee for Audrey Lee Congdon Revocable Trust dated 2/17/05
Common Stock               58,198 I By wife as trustee for Irrevocable Trust Agreement dated 12/18/98 fbo Megan Yowell
Common Stock               58,198 I By wife as trustee for Irrevocable Trust Agreement dated 12/18/98 fbo Seth Yowell
Common Stock               104,856 D  
Common Stock               257,188 I As trustee for Audrey L. Congdon Irrevocable Trust No. 1 dated 12/1/92
Common Stock               25,937 I By 401(k) plan
Common Stock               8,929 I By wife
Common Stock               430,651 I By wife as co-trustee of the Earl E. Congdon GRAT Remainder Trust
Common Stock               150,000 I By wife as trustee for Audrey L. Congdon February 2010 Grantor Retained Annuitiy Trust
Common Stock 09/16/2010   S(1)   3,927 D $ 25.962 (3) 142,602 I As co-trustee of the Seth Morgan Yowell Irrevocable Declaration of Trust
Common Stock 09/16/2010   S(1)   1,183 D $ 26.1053 (4) 141,419 I As co-trustee of the Seth Morgan Yowell Irrevocable Declaration of Trust
Common Stock 09/16/2010   S(1)   3,927 D $ 25.962 (3) 142,602 I As co-trustee of the Megan Elise Yowell Irrevocable Declaration of Trust
Common Stock 09/16/2010   S(1)   1,183 D $ 26.1053 (4) 141,419 I As co-trustee of the Megan Elise Yowell Irrevocable Declaration of Trust
Common Stock 09/16/2010   S(1)   205 D $ 25.962 (3) 46,458 I By Audrey L. Congdon Irrevocable Trust No. 2 dated 5/28/04 (David Congdon, Trustee)
Common Stock 09/16/2010   S(1)   62 D $ 26.1053 (4) 46,396 I By Audrey L. Congdon Irrevocable Trust No. 2 dated 5/28/04 (David Congdon, Trustee)
Common Stock 09/16/2010   S(1)   7,978 D $ 25.962 (3) 821,849 I By wife as trustee for Audrey Lee Congdon Revocable Trust dated 2/17/05
Common Stock 09/16/2010   S(1)   2,403 D $ 26.1053 (4) 819,446 I By wife as trustee for Audrey Lee Congdon Revocable Trust dated 2/17/05

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
YOWELL JOHN B
C/O OLD DOMINION FREIGHT LINE, INC.
500 OLD DOMINION WAY
THOMASVILLE, NC 27360
    X   Executive VP and COO Member of Section 13(d) group

Signatures

 /s/ Joel B. McCarty, Jr., by Power of Attorney   09/17/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 30, 2010.
(2) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.33 to $25.41, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
(3) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.33 to $26.20, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
(4) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $26.00 to $26.20, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
 
Remarks:
The reporting person may be deemed to be a member of a "group" for purposes of Section 13(d) of the Exchange Act.  The other members of the Section 13(d) group are identified on a Schedule 13D filed with the Securities and Exchange Commission on September 9, 2010.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.