Filed pursuant to Rule 424(b)(3) Registration No. 333-88834 Prospectus Supplement No. 2 dated June 19, 2002 (To Prospectus dated May 31, 2002) $3,950,000,000 Amgen Inc. Liquid Yield Option(TM) Notes due 2032 (Zero Coupon--Senior) and Shares of Common Stock Issuable Upon Conversion of the Liquid Yield Option(TM) Notes This document supplements the prospectus dated May 31, 2002, as amended and supplemented through the date hereof, relating to the resale by the holders of Liquid Yield Option(TM) Notes (Zero Coupon--Senior) (the "LYONs") due March 1, 2032 and the shares of our common stock into which the LYONs are convertible. This prospectus supplement is incorporated by reference into, and should be read in conjunction with, the prospectus dated May 31, 2002, including any amendments or supplements to it. This prospectus supplement is not complete without, and may not be delivered or utilized except in connection with, the prospectus, including any amendments or supplements to it. The table presented below sets forth information as of the date of this prospectus supplement about the principal amount at maturity of the LYONs and the underlying common stock beneficially owned by each selling security holder that may be offered using the prospectus. All of the information set forth in the table has been provided by the selling security holders on or prior to the date of this prospectus supplement and, to our knowledge, is true and correct as of the date of this prospectus supplement. However, the selling security holders may have sold, transferred or otherwise disposed of all or a portion of their notes since the date on which they provided the information regarding their notes. The table of selling security holders contained on pages 42-45 of the prospectus dated May 31, 2002 is hereby amended and replaced by the table set forth below. Principal Amount of Shares of LYONs Stock LYONs Common Owned Owned Beneficially Stock Common After After Owned and Beneficially Stock Completion Completion Material Name Offered Owned Offered/(1)/ of Offering/(2)/ of Offering/(2)/ Relationship/(3)/ ------------------- -------------- -------------- --------------- ------------------ ------------------ ------------------- 02 Convertible Master Fund, Ltd............ 22,712,000 201,230.6 201,230.6 -0- - None 02 Mac 13 Ltd......... 5,521,000 48,916.6 48,916.6 -0- - None 02 Master Fund, Ltd... 247,824,000 2,195,745.4 2,195,745.4 -0- - None 1 1976 Distribution Trust FBO A.R. Lauder / Zinterhofer .............................. 18,000 159.5 159.5 -0- - None 1976 Distribution Trust FBO Jane A. Lauder....... ............................ 35,000 310.1 310.1 -0- - None 2000 Revocable Trust FBO A.R. Lauder / Zinterhofer .............................. 18,000 159.5 159.5 -0- - None Absolute Return Fund Ltd. ................. 5,941,000 52,637.9 52,637.9 -0- - None Advent Convertible Master Cayman L.P. ..... 6,242,000 55,304.7 55,304.7 -0- - None Aid Association for Lutherans, as successor to Lutheran Brotherhood ........ 11,000,000 97,461.1 97,461.1 -0- - None Akela Capital Master Fund, LLC............. 2,000,000 17,720.2 17,720.2 -0- - None Allentown City Firefighters Pension Plan... 62,000 549.3 549.3 -0- - None Allentown City Officers & Employees Pension Fund.............................. 45,000 398.7 398.7 -0- - None Allentown City Police Pension Plan......... 74,000 655.7 655.7 -0- - None Allgemeine Pensionskasse der Swissair Group..................................... 1,200,000 10,632.1 10,632.1 -0- - None Allstate Insurance Company................. 21,900,000/(4)/ 478,336.2/(4)/ 194,036.2/(4)/ -0-/(4)/ 284,300/(4)/ None Allstate Life Insurance Company............ 21,900,000/(4)/ 478,336.2/(4)/ 194,036.2/(4)/ -0-/(4)/ 284,300/(4)/ None Alpha US Sub Fund 4, LLC................... 675,000 5,980.6 5,980.6 -0- - None Alpha U.S. Sub Fund VIII, LLC.............. 2,300,000 20,378.2 20,378.2 -0- - None American Motorist Insurance Company........ 1,396,000 12,368.7 12,368.7 -0- - None Amerisure Mutual Insurance Company......... 975,000 8,638.6 8,638.6 -0- - None Arapahoe County Colorado................... 135,000 1,196.1 1,196.1 -0- - None 2 Argent Classic Convertible Arbitrage Fund L.P.......... 4,500,000 39,870.5 39,870.5 -0- - None Argent Classic Convertible Arbitrage Fund (Bermuda) Ltd......................... 6,000,000 53,160.6 53,160.6 -0- - None Argent LowLev Convertible Arbitrage Fund Ltd ......... 13,500,000 119,611.4 119,611.4 -0- - None Aristeia International Limited .................... 26,950,000 238,779.7 238,779.7 -0- - None Aristeia Trading LLC......... 8,050,000 71,323.8 71,323.8 -0- - None Arlington County Employees Retirement System........... 1,470,000 13,024.4 13,024.4 -0- - None Associated Electric & Gas Insurance Services Limited .................... 3,000,000 26,580.3 26,580.3 -0- - None Auspicis Ltd................. 430,000 3,809.9 3,809.9 -0- - None Banc of America Securities LLC......................... 21,281,000 188,551.8 188,551.8 -0- - None Bank Austria Cayman Islands, Ltd......................... 4,500,000 39,870.5 39,870.5 -0- - None Bank of America Pension Plan........................ 2,500,000 22,150.3 22,150.3 -0- - None Bank von Ernst & Cie AG...... 150,000 1,329.0 1,329.0 -0- - None Barclays Global Investors Ltd. ....................... 1,500,000 13,290.2 13,290.2 -0- - None Beamtenversicherung-skasse des Kantons Zurich.......... 10,900,000 96,575.1 96,575.1 -0- - None Bear Stearns International Limited..................... 21,835,000 193,460.3 193,460.3 -0- - None Bear, Stearns & Co. Inc...... 9,500,000 84,171.0 84,171.0 -0- - None BGI Global Investors c/o Forest Investment Mngt. L.L.C. ..................... 685,000 6,069.2 6,069.2 -0- - None Black Diamond Capital I, Ltd......................... 2,432,000 21,547.8 21,547.8 -0- - None Black Diamond Convertible Offshore LDC................ 15,296,000 135,524.1 135,524.1 -0- - None Black Diamond Offshore Ltd......................... 8,647,000 76,613.3 76,613.3 -0- - None 3 British Virgin Islands Social Security Board..... ............................... 196,000 1,736.6 1,736.6 -0- - None Canyon Capital Arbitrage Masterfund, Ltd... 3,750,000 33,225.4 33,225.4 -0- - None Canyon Mac 18, Ltd. (RMF).................. 625,000 5,537.6 5,537.6 -0- - None Canyon Value Realization Fund (Cayman), Ltd....................................... 5,625,000 49,838.1 49,838.1 -0- - None Canyon Value Realization Fund, L.P......... 2,500,000 22,150.3 22,150.3 -0- - None CDC Financial Products, Inc. .............. 20,000,000 177,202.0 177,202.0 -0- - None CDC Ixis Paris............................. 20,000,000 177,202.0 177,202.0 -0- - None Circlet (IMA) Ltd.......................... 1,500,000 13,290.2 13,290.2 -0- - None City of New Orleans........................ 558,000 4,943.9 4,943.9 -0- - None City University of New York................ 335,000 2,968.1 2,968.1 -0- - None Clinton Convertible Managed Trading Account 1 Limited......................... 4,250,000 37,655.4 37,655.4 -0- - None Clinton Multistrategy Master Fund, Ltd. ... 18,225,000 161,475.3 161,475.3 -0- - None Clinton Riverside Convertible Portfolio Limited................................... 20,025,000 177,423.5 177,423.5 -0- - None Cobra Master Fund, Ltd..................... 1,500,000 13,290.2 13,290.2 -0- - None Continental Assurance Company on behalf of its Separate Account E ................... 7,200,000 63,792.7 63,792.7 -0- - None Continental Casualty Company............... 44,800,000 396,932.5 396,932.5 -0- - None Credit Industriel D'Alsace Et De Lorraine.. 25,400,000 225,046.5 225,046.5 -0- - None Credit Lyonnais SEC USA.................... 28,000,000 248,082.8 248,082.8 -0- - None Credit Suisse First Boston Europe Ltd...... 278,650,000 2,468,866.9 2,468,866.9 -0- - None 4 DaimlerChrysler Corp Emp. #1 Pension Plan dtd 4/1/89 ............................... 13,980,000 123,864.2 123,864.2 -0- - None Deephaven Domestic Convertible Trading Ltd....................................... 165,850,000 1,469,447.6 1,469,447.6 -0- - None Deeprock & Co.............................. 3,000,000 26,580.3 26,580.3 -0- - None Deutsche Bank Securities Inc............... 349,900,000 3,100,149.0 3,100,149.0 -0- - None DKR Fixed Income Holding Fund Ltd.......... 3,000,000 26,580.3 26,580.3 -0- - None Double Black Diamond Offshore LDC.......... 50,469,000 447,160.4 447,160.4 -0- - None First Union Securities Inc................. 20,000,000 177,202.0 177,202.0 -0- - None Forest Alternative Strategies II........... 186,000 1,648.0 1,648.0 -0- - None Forest Fulcrum Fund L.L.P.................. 2,592,000 22,965.4 22,965.4 -0- - None Forest Global Convertible Fund Series A-5.. 9,682,000 85,783.5 85,783.5 -0- - None Franklin and Marshall College.............. 785,000 6,955.2 6,955.2 -0- - None Gaia Offshore Master Fund Ltd.............. 6,450,000 57,147.6 57,147.6 -0- - None GDO Equity Arbitrage Master Fund........... 7,500,000 66,450.8 66,450.8 -0- - None Gemini Sammel Stiftung Zur Forderung der Personalvorsorge ......................... 450,000 3,987.0 3,987.0 -0- - None Georgia Municipal Employee Benefit System.. 1,500,000 13,290.2 13,290.2 -0- - None Global Bermuda Limited Partnership......... 7,000,000 62,020.7 62,020.7 -0- - None GM Employees Global Group Pension Trust.... 2,000,000 17,720.2 17,720.2 -0- - None Goldman Sachs & Co. Profit Sharing Master Trust..................................... 5,371,000 47,587.6 47,587.6 -0- - None Goldman Sachs and Company.................. 20,460,000 181,277.6 181,277.6 -0- - None 5 The Grable Foundation........ 261,000 2,312.5 2,312.5 -0- - None Grady Hospital Foundation.... 294,000 2,604.9 2,604.9 -0- - None Granville Capital Corporation................. 45,000,000 398,704.5 398,704.5 -0- - None Hamilton Multi-Strategy Master Fund, LP............. 6,000,000 53,160.6 53,160.6 -0- - None HBK Master Fund, L.P......... 17,000,000 172,821.7 150,621.7 -0- 22,200 None HFR CA Select Fund........... 700,000 6,202.0 6,202.0 -0- - None HFR Convertible Arbitrage Account..................... 581,000 5,147.7 5,147.7 -0- - None Highbridge International LLC......................... 148,150,000 1,312,623.8 1,312,623.8 -0- - None HSBC Trustee, Zola Managed Trust....................... 400,000 3,544.0 3,544.0 -0- - None Independence Blue Cross...... 901,000 7,983.0 7,983.0 -0- - None ING Convertible Fund......... 3,960,000 35,086.0 35,086.0 -0- - None ING VP Convertible Fund...... 40,000 354.4 354.4 -0- - None Jersey (IMA) Ltd............. 3,000,000 26,580.3 26,580.3 -0- - None JP Morgan Securities Inc..... 284,000,000 2,557,109.4 2,516,268.4 -0- 40,841 None KBC Financial Products (Cayman Island) Limited..... 52,000,000 460,725.2 460,725.2 -0- - None KBC Financial Products USA Inc......................... 4,480,000 39,693.2 39,693.2 -0- - None Lakeshore International, Ltd......................... 28,000,000 248,082.8 248,082.8 -0- - None Lehman Brothers Inc.......... 10,000,000 88,601.0 88,601.0 -0- - None Lexington (IMA) Limited...... 10,051,000 89,052.9 89,052.9 -0- - None Liberty View Fund LLC........ 2,000,000 17,720.2 17,720.2 -0- - None Liberty View Funds L.P....... 9,000,000 79,740.9 79,740.9 -0- - None Liberty View Global Volatility Fund............. 26,000,000 230,362.6 230,362.6 -0- - None LLT Limited.................. 685,000 6,069.2 6,069.2 -0- - None Lyxor........................ 1,185,000 10,499.2 10,499.2 -0- - None Lyxor Master Fund............ 1,550,000 13,733.2 13,733.2 -0- - None 6 Lyxor Master Fund c/o Forest Investment Mngt. L.L.C............................... 2,700,000 23,922.3 23,922.3 -0- - None Lyxor Master Fund, c/o Zola Capital Management, LLC.......................... 4,750,000 42,085.5 42,085.5 -0- - None Lyxor Master Fund Ref: Argent/LowLev CB.... 3,000,000 26,580.3 26,580.3 -0- - None Marathon Global Convertible Master Fund, Ltd....................................... 11,500,000 101,891.2 101,891.2 -0- - None McMahan Securities Co. L.P................. 4,000,000 35,440.4 35,440.4 -0- - None Merrill Lynch Insurance Group.............. 725,000 6,423.6 6,423.6 -0- - None Merrill Lynch International Limited........ 6,000,000 232,719.6 53,160.6 -0- 179,559 None Merrill Lynch, Pierce, Fenner & Smith, Inc....................................... 77,983,000 690,937.2 690,937.2 -0- - None Minnesota Power and Light.................. 171,000 1,515.1 1,515.1 -0- - None MLQA Convertible Securities Arbitrage, Ltd. ..................................... 20,000,000 177,202.0 177,202.0 -0- - None Morgan Stanley & Co. ...................... 40,000,000 354,404.0 354,404.0 -0- - None Municipal Employees........................ 503,000 4,456.6 4,456.6 -0- - None New Orleans Firefighters Pension / Relief Fund...................................... 302,000 2,675.8 2,675.8 -0- - None Nicholas Applegate Investment Grade Convertible.............................. 37,000 327.8 327.8 -0- - None NMS Services (Cayman) Inc.................. 50,000,000 443,005.0 443,005.0 -0- - Occidental Petroleum Corporation........... 569,000 5,041.4 5,041.4 -0- - None Ohio Bureau of Workers Compensation........ 389,000 3,446.6 3,446.6 -0- - None Pensionskasse Ciba Specialty Chemicals..... 1,900,000 16,834.2 16,834.2 -0- - None Pensionskasse der Antalis AG............... 220,000 1,949.2 1,949.2 -0- - None Pensionskasse der EMS-Chemie AG............ 270,000 2,392.2 2,392.2 -0- - None Pensionskasse der EMS-Chemie AG Domat...... 270,000 2,392.2 2,392.2 -0- - None 7 Pensionskasse der EMS-Dottikon AG ........... 400,000 3,544.0 3,544.0 -0- - None Pensionskasse der Lonza AG .................. 500,000 4,430.1 4,430.1 -0- - None Pensionskasse der Rockwell Automation AG ............. 270,000 2,392.2 2,392.2 -0- - None Pensionskasse Pluss- Staufer AG ................ 250,000 2,215.0 2,215.0 -0- - None Pensionskasse Vantico ....... 380,000 3,366.8 3,366.8 -0- - None Peoples Benefit Life Insurance Company Teamsters ................. 7,500,000 66,450.8 66,450.8 -0- - None Performa Institutional Fund US Dollar Convertible Bond .......... 150,000 1,329.0 1,329.0 -0- - None Policeman and Firemen Retirement System of the City of Detroit ................... 1,380,000 12,226.9 12,226.9 -0- - None Pro-mutual .................. 1,654,000 14,654.6 14,654.6 -0- - None Quattro Fund ................ 8,910,000 78,943.5 78,943.5 -0- - None Ram Trading ................. 7,000,000 62,020.7 62,020.7 -0- - None Ramius Capital Group ........ 500,000 4,430.1 4,430.1 -0- - None Ramius LP ................... 1,000,000 8,860.1 8,860.1 -0- - None RBC Capital Services c/o Forest Investment Mngt. L.L.C. .................... 382,000 3,384.6 3,384.6 -0- - None RCG Baldwin LP .............. 1,500,000 13,290.2 13,290.2 -0- - None RCG Halifax Master Fund, Ltd. ................ 1,500,000 13,290.2 13,290.2 -0- - None RCG Latitude Master Fund, Ltd. ................ 2,500,000 22,150.3 22,150.3 -0- - None RCG Multi Strategy, LP ...... 3,000,000 26,580.3 26,580.3 -0- - None Relay 11 Holdings c/o Forest Investment Mngt. L.L.C. .............. 345,000 3,056.7 3,056.7 -0- - None Retail Clerks Pension Trust 2 ................... 2,000,000 17,720.2 17,720.2 -0- - None SAC Capital Associates, LLC ........... 27,500,000 343,652.8 243,652.8 -0- 100,000 None Sagamore Hill Hub Fund Ltd. ................. 30,500,000 270,233.1 270,233.1 -0- - None Salomon Smith Barney Inc. ...................... 31,836,000 282,070.1 282,070.1 -0- - None 8 San Diego County Employees Retirement Association .............. 2,000,000 17,720.2 17,720.2 -0- - None Serena Limited ............. 2,080,000 18,429.0 18,429.0 -0- - None Shell Pension Trust ........ 871,000 7,717.2 7,717.2 -0- - None St. Albans Partners Ltd. ... 5,000,000 44,300.5 44,300.5 -0- - None State of Maryland Retirement Agency ........ 7,078,000 62,711.8 62,711.8 -0- - None State of Mississippi Health Care Trust Fund ... 825,000 7,309.6 7,309.6 -0- - None State Street Bank Custodian for GE Pension Trust ............ 6,405,000 56,748.9 56,748.9 -0- - None Susquehanna Capital Group .................... 5,000,000 44,300.5 44,300.5 -0- - None Sylvan (IMA) Ltd. c/o Forest Investment Mngt. L.L.C. ............. 1,520,000 13,467.4 13,467.4 -0- - None Tag Associates ............. 151,000 1,337.9 1,337.9 -0- - None TD Securities (USA) Inc. ... 65,000,000 575,906.5 575,906.5 -0- - None Teachers Insurance & Annuity Association ...... 16,000,000 141,761.6 141,761.6 -0- - None TQA Master Fund, Ltd. ...... 7,000,000 62,020.7 62,020.7 -0- - None TQA Master Plus Fund, Ltd. ..................... 3,000,000 26,580.3 26,580.3 -0- - None Tribecca Investments, LLC ...................... 60,000,000 531,606.0 531,606.0 -0- - None Trustmark Insurance ........ 760,000 6,733.7 6,733.7 -0- - None UBS AG London .............. 144,000,000 1,275,854.4 1,275,854.4 -0- - None UBS O'Connor LLC F/B/O O'Connor Global Convertible Portfolio ................ 750,000 6,645.1 6,645.1 -0- - None UBS O'Connor LLC F/B/O UBS Global Equity Arbitrage Master Ltd. .............. 35,000,000 310,103.5 310,103.5 -0- - None 9 UBS Warburg LLC ............. 24,060,000 213,174.0 213,174.0 -0- - None UFJ Investments Asia Ltd .... 25,000,000 221,502.5 221,502.5 -0- - None US Bancorp Piper Jaffray .... 5,707,000 50,564.6 50,564.6 -0- - None Von Ernst Global Portfolio - Convertible Bond Fund ..... 1,300,000 11,518.1 11,518.1 -0- - None Wachovia Bank National Association ............... 20,000,000 177,202.0 177,202.0 -0- - None Wachovia Securities International Ltd. ........ 31,000,000 274,663.1 274,663.1 -0- - None White River Securities LLC ....................... 9,500,000 84,171.0 84,171.0 -0- - None Worldwide Transactions Ltd. ...................... 2,156,000 19,102.4 19,102.4 -0- - None Yield Strategies Fund I, L.P. ................... 5,000,000 44,300.5 44,300.5 -0- - None Yield Strategies Fund II, L.P. .................. 5,000,000 44,300.5 44,300.5 -0- - None Zazove Convertible Arbitrage Fund L.P. ....... 500,000 4,430.1 4,430.1 -0- - None Zazove Hedged Convertible Fund L.P. ..... 2,800,000 24,808.3 24,808.3 -0- - None Zazove Income Fund L.P. ..... 2,000,000 17,720.2 17,720.2 -0- - None Zola Partners, L.P. ......... 7,250,000 64,235.7 64,235.7 -0- - None Zurich Institutional Benchmark Management c/o Quattro Fund .......... 3,590,000 31,807.8 31,807.8 -0- - None Zurich Institutional Benchmarks Master Fund Ltd. ................. 2,800,000 24,808.3 24,808.3 -0- - None Zurich Master Hedge Fund c/o Forest Investments Mngt. L.L.C. .................... 1,223,000 10,835.9 10,835.9 -0- - None Other ....................... 780,677,000 6,916,874.9 6,916,874.9 -0- - None --------------------------------- (1) Represents shares of common stock issuable upon conversion of LYONs that are beneficially owned and offered by the selling security holder. (2) Assumes that all of the LYONs and/or all of the common stock into which the LYONs are convertible are sold. (3) Includes any position, office or other material relationship which the selling security holder has had within the past three years with Amgen or any of its predecessors or affiliates. 10 (4) Allstate Insurance Company and Allstate Life Insurance Company are affiliated entities. Allstate Insurance Company is the record owner of $4,000,000 principal amount of LYONs and Allstate Life Insurance Company is the record owner of $17,900,000 principal amount of LYONs. Aside from the LYONs and the common stock into which the LYONs are convertible, Allstate Insurance Company is the record owner of 180,300 shares of our common stock and Allstate Insurance Company and its affiliates beneficially own an aggregate of 284,300 shares of our common stock. See "Risk Factors" section beginning on page 8 of the prospectus to read about factors you should consider before purchasing the LYONs or our common stock. Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus. Any representation to the contrary is a criminal offense. The date of this prospectus supplement is June 19, 2002. (TM) Trademark of Merrill Lynch & Co., Inc. 11