SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  SCHEDULE 13G
                                 (Rule 13d-102)


            INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
          TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED
                           PURSUANT TO RULE 13d-2(b).
                               (Amendment No.__)*


                            LYNX THERAPEUTICS, INC.
--------------------------------------------------------------------------------
                                (Name of Issuer)


                     Common Stock, par value $0.01 per share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    551812 30 8
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                  April 14, 2004
--------------------------------------------------------------------------------
            (Date of Event Which Requires Filing of this Statement)



Check  the appropriate box to designate the rule pursuant to which this Schedule
is  filed:


     [ ]   Rule 13d-1(b)
     [X]   Rule 13d-1(c)
     [ ]   Rule 13d-1(d)


     *The  remainder  of  this  cover  page  shall be filled out for a reporting
person's  initial  filing  on  this  form  with  respect to the subject class of
securities,  and for any subsequent amendment containing information which would
alter  the  disclosures  provided  in  a  prior  cover  page.

     The  information  required in the remainder of this cover page shall not be
deemed  to  be  "filed" for the purpose of Section 18 of the Securities Exchange
Act  of  1934 ("Act") or otherwise subject to the liabilities of that section of
the  Act,  but shall be subject to all other provisions of the Act (however, see
the  Notes).


                                                                     Page 1 of 5

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CUSIP No. 551812 30 8                   13G                Page 2---of---5 Pages
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     1     NAMES OF REPORTING PERSONS/I.R.S.  IDENTIFICATION NOS. OF ABOVE
           PERSONS (Entities Only)

           Manteia SA
--------------------------------------------------------------------------------
     2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
           (See Instructions)                                           (a)  [ ]
                                                                        (b)  [ ]

--------------------------------------------------------------------------------
     3     SEC USE ONLY

--------------------------------------------------------------------------------
     4     CITIZENSHIP OR PLACE OF ORGANIZATION

           Switzerland
--------------------------------------------------------------------------------
 NUMBER  OF         5     SOLE VOTING POWER

                          540,058
   SHARES         --------------------------------------------------------------
                    6     SHARED VOTING POWER

BENEFICIALLY              N/A
                  --------------------------------------------------------------
OWNED BY EACH       7     SOLE DISPOSITIVE POWER

                          540,058
  REPORTING       --------------------------------------------------------------
                    8     SHARED DISPOSITIVE POWER

PERSON WITH               N/A
--------------------------------------------------------------------------------
      9     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

            540,058
--------------------------------------------------------------------------------
     10     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
            SHARES (See Instructions)                                        [ ]

--------------------------------------------------------------------------------
     11     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

            7.2%
--------------------------------------------------------------------------------
     12     TYPE OF REPORTING PERSON (See Instructions)

            CO
--------------------------------------------------------------------------------



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CUSIP No. 551812 30 8                  13G                 Page 3---of---5 Pages
----------------------                                    ----------------------



ITEM  1(a).    NAME  OF  ISSUER:

               Lynx Therapeutics, Inc.

ITEM  1(b).    ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

               25861 Industrial Boulevard
               Hayward, CA 94545

ITEM  2(a).    NAME OF PERSON FILING:

               Manteia SA

ITEM  2(b).    ADDRESS  OF  PRINCIPAL  BUSINESS OFFICE OR, IF NONE, RESIDENCE:

               Manteia SA
               Zone Industrielle
               1267 Coinsins
               Switzerland

ITEM  2(c).    CITIZENSHIP:

               A stock company organized under the laws of Switzerland.

ITEM  2(d).    TITLE OF CLASS OF SECURITIES:

               Common Stock, par value $0.01 per share

ITEM  2(e).    CUSIP  NUMBER:

               551812308

ITEM 3.        IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(b), OR 13D-2(b)
               OR (c), CHECK WHETHER THE PERSON FILING IS A: N/A

               Not applicable.

ITEM  4.       OWNERSHIP.

     The ownership percentage set forth below is based on 7,527,538 shares of
common stock outstanding as of April 14, 2004.

     (a)  Amount beneficially owned: 540,058

     (b)  Percent  of  class:  7.2%

     (c)  Number of shares as to which such person has:

          (i)   Sole power to vote or to direct the vote: 540,058

          (ii)  Shared power to vote or to direct the vote: N/A

          (iii) Sole power to dispose or to direct the disposition of: 540,058



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CUSIP No. 551812 30 8                  13G                 Page 4---of---5 Pages
----------------------                                    ----------------------


          (iv)  Shared power to dispose or to direct the disposition of: N/A

ITEM  5.     OWNERSHIP  OF  FIVE  PERCENT  OR  LESS  OF  A  CLASS.

             Not applicable.

ITEM  6.     OWNERSHIP  OF  MORE  THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

             Not applicable.

ITEM  7.     IDENTIFICATION  AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
             THE  SECURITY  BEING  REPORTED  ON  BY  THE PARENT HOLDING COMPANY
             OR CONTROL PERSON.

             Not applicable.

ITEM  8.     IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

             Not applicable.

ITEM  9.     NOTICE OF DISSOLUTION OF GROUP.

             Not applicable.

ITEM  10.    CERTIFICATIONS.

             By signing below, I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are not held for
the purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.



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CUSIP No. 551812 30 8                  13G                 Page 5---of---5 Pages
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                                   SIGNATURES

     After  reasonable  inquiry  and  to  the best of my knowledge and belief, I
certify  that  the information set forth in this statement is true, complete and
correct.


Dated:  April 14, 2004



                                    Manteia SA



                                    /s/  Francois Naef
                                    --------------------------------------
                                    By: Francois Naef
                                    Title: Director