UNITED STATES
                  SECURITIES AND EXCHANGE COMMISSION
                         Washington, DC 20549

                             FORM 12b-25           SEC File Number: 0-24930

                                                   CUSIP Number: 232930 10 7

                     NOTIFICATION OF LATE FILING

(Check One): Form 10-K   Form 20-F   Form 11-K   [x] Form 10-Q   Form N-SAR

For Period Ended:  June 30, 2004

     Transition  Report  on Form 10-K
     Transition  Report on Form 20-F
     Transition  Report  on Form  11-K
     Transition  Report on Form 10-Q
     Transition Report on Form N-SAR

For the Transition Period Ended:

Nothing  in this  form  shall be  construed  to imply  that the  Commission  has
verified any information contained herein.

If the notification  relates to a portion of the filing checked above,  identify
the Item(s) to which the notification relates:

PART I - REGISTRANT INFORMATION

Full Name of Registrant:

             CTD HOLDINGS, INC

Former Name if Applicable:

              N/A

Address of Principal Executive Office (Street and Number)

              27317 N.W. 78th AVENUE

City State and Zip Code

             HIGH SPRINGS FL 32643

PART II - RULES 12b-25(b) AND (c)

If the subject report could not be filed without  unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

         (a) The reasons described in reasonable detail in Part III of this form
             could not be eliminated without unreasonable effort or expense;

         (b) The subject annual report, semi-annual report, transition report on
             Form 10-K, Form 20-F, 11-K or Form N-SAR or portion  thereof,  will
             be filed on or before the  fifteenth  calendar  day  following  the
             prescribed due date; or the subject quarterly report or transition
   [X]       report on Form 10-Q, or portion  thereof will be filed
             on or before the fifth  calendar day following the  prescribed due
             date; and

         (c) The  accountant's  statement  or  other  exhibit  required  by Rule
             12b-25(c) has been attached if applicable.

PART III - NARRATIVE

State below in reasonable  detail the reasons why Forms 10-K,  20-F, 11-K, 10-Q,
N-SAR, or the transition  report or portion  thereof,  could not be filed within
the prescribed period of time.

Necessary  accounting  information  is being revised and is not available at the
time of filing.

PART IV - OTHER INFORMATION

(1)  Name  and  telephone  number  of  person  to  contact  in  regard  to  this
notification:

                Bruce Brashear, Esq.               352-336-0800

(2) Have all other  periodic  reports  required under Section 13 of 15(d) of the
Securities and Exchange Act of 1934 or Section 30 of the Investment  Company Act
of 1940  during the  preceding  12 months or for such  shorter  period  that the
registrant  was  required to file such  report(s)  been filed?  If answer is no,
identify report(s). Yes

(3) Is it anticipated that any significant  change in results of operations from
the  corresponding  period for the last  fiscal  year will be  reflected  by the
earnings statements to be included in the subject report or portion thereof? Yes

If so, attach an explanation of the  anticipated  change,  both  narratively and
quantitatively, and, if appropriate, state the reasons why a reasonable estimate
of the results cannot be made.

The  Company  anticipates  a charge  of  approximately  $300,000  from  expenses
associated with the future disposition of a sports card memorabilia collection.

Name of Registrant as Specified in Charter:   CTD HOLDINGS, INC

has  caused  this  notification  to be signed on its  behalf by the  undersigned
hereunto duly authorized.
                                                       /S/ C.E. RICK STRATTAN
Date: August 13, 2004                              By: C.E. RICK STRATTAN
                                                       President, CEO

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly  authorized  representative.  The name and title of the person
signing the form shall be typed or printed  beneath the signature.  If the state
is signed on behalf of the  registrant  by an authorized  representative  (other
than an executive officer),  evidence of the representative's  authority to sign
on behalf of the registrant shall be filed with the form.