FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person *   Licholai Gregory P 2. Date of Event Requiring Statement (Month/Day/Year) 05/30/2007 3. Issuer Name and Ticker or Trading Symbol AMICUS THERAPEUTICS INC [FOLD] (Last) (First) (Middle) C/O AMICUS THERAPEUTICS, INC., 6 CEDAR BROOK DRIVE 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) VP, Medical Affairs 5. If Amendment, Date Original Filed(Month/Day/Year) (Street) CRANBURY, NJ 08512 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5) Common Stock 20,152 D   Common Stock 6,666 (1) I By Gregory P. Licholai 2006 Grantor Retained Annuity Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Employee Stock Option (right to buy)	  (2)	01/03/2015	Common Stock	53,638	$ 0.638	D	Â
Employee Stock Option (right to buy)	  (3)	10/20/2015	Common Stock	26,667	$ 5.33	D	Â
Employee Stock Option (right to buy)	  (4)	02/28/2016	Common Stock	20,000	$ 5.33	D	Â
Employee Stock Option (right to buy)	  (5)	04/25/2017	Common Stock	13,334	$ 13.43	D	Â

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Licholai Gregory P C/O AMICUS THERAPEUTICS, INC. 6 CEDAR BROOK DRIVE CRANBURY, NJ 08512	Â	Â	  VP, Medical Affairs	Â

Signatures

/s/ Douglas A. Branch, Attorney-in-fact		05/30/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These shares are held by the Gregory P. Licholai 2006 Grantor Retained Annuity Trust. Mr. Licholai disclaims beneficial ownership of the shares held by the Gregory P. Licholai 2006 Grantor Retained Annuity Trust except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for the purposes of section 16 or for any other purpose.
(2)	These options vest and become exercisable in a series of installments. The first installment, which consisted of 25% of the total aggregate number of options granted, vested on January 3, 2006. The remaining options vest and become exercisable in a series of thirty-five successive equal monthly installments of 1,677 shares, beginning on February 3, 2006, with a final installment of 1,646 shares vesting on January 3, 2009.
(3)	These options vest and become exercisable in a series of installments. The first installment, which consisted of 25% of the total aggregate number of options granted, vested on October 20, 2006. The remaining options vest and become exercisable in a series of thirty-five successive equal monthly installments of 556 shares, beginning on November 1, 2006, with a final installment of 540 shares vesting on October 1, 2009.
(4)	These options vest and become exercisable in a series of installments. The first installment, which consisted of 25% of the total aggregate number of options granted, vested on February 28, 2007. The remaining options vest and become exercisable in a series of thirty-five successive equal monthly installments of 417 shares, beginning on March 1, 2007 with a final installment of 405 shares vesting on February 1, 2010.
(5)	These options vest and become exercisable in a series of installments. The first installment, which consists of 25% of the total aggregate number of options granted, will vest on April 25, 2008. The remaining options vest and become exercisable in a series of thirty-five successive equal monthly installments of 278 shares, beginning on May 1, 2008, with a final installment of 270 shares vesting on April 1, 2011.

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