UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 12b-25

                        Commission File Number: 01-28911

                           Notification of Late Filing


(Check one)

|_| Form 10-K         |_| Form 11-K         | | Form 10-Q        |_| Form N-SAR
|X| Form 10-KSB

For Period Ended: December 31, 2005

      [ ] Transition Report on Form 10-K
      [ ] Transition Report on Form 20-F
      [ ] Transition Report on Form 11-K
      [ ] Transition Report on Form 10-Q
      [ ] Transition Report on Form N-SAR

      For the Transition Period Ended: N/A

      If the notification relates to a portion of the filing checked above,
identify the item(s) to which the notification relates:

                                     PART I
                             REGISTRANT INFORMATION

                      MICRO BIO-MEDICAL WASTE SYSTEMS, INC.
                      -------------------------------------
                             Full name of Registrant

                            -------------------------
                            Former Name if Applicable

                              27430 Riverside Lane
                              --------------------
            Address of principal executive offices(Street and Number)

                           Valencia, California 91354
                           --------------------------
                            City, State and Zip Code

                                     PART II
                             RULES 12b-25(b) and (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed.  (Check appropriate box.) [ ] Yes [ ] No

[X]   (a) The reasons described in reasonable detail in Part III of this form
      could not be eliminated without unreasonable effort or expense.

[X]   (b) The subject annual report, semi-annual report, transition report on
      Form 10-K, 20-F, 11-K or N-SAR, or portion thereof, will be filed on or
      before the 15th calendar day following the prescribed due date; or the



      subject quarterly report or transition report on Form 10-Q, or portion
      thereof, will be filed on or before the fifth calendar day following the
      prescribed due date.

[ ]   The accountant's statement or other exhibit required by Rule 12b-25(c) has
      been attached if applicable.

                                    PART III
                                    NARRATIVE

State below in reasonable detail the reasons why Form 10-K, 11-K, 20-F, 10-Q, N-
SAR, or the transition report or portion thereof, could not be filed within the
prescribed time period.

      The Registrant's quarterly report on Form 10-KSB will be filed on or
before the fifteenth calendar following the prescribed due date. The reason for
the delay is that the Registrant is waiting for certain information from a third
party.

                                     PART IV
                                OTHER INFORMATION

(1) Name and telephone number of person to contact in regard to this
notification:

Charles Smith                       (661) 287-3772
(Name)                              (Area Code)(Telephone Number)


(2)   Have all other periodic reports required under Section 13 or 15(d) of the
      Securities Exchange Act of 1934 or Section 30 of the Investment Company
      Act of 1940 during the preceding 12 months or such shorter period that the
      registrant was required to file such report(s) been filed? If answer is
      no, identify report(s). [x] Yes [ ] No

(3)   Is it anticipated that any significant change in results of operation for
      the corresponding period for the last fiscal year will be reflected by the
      earnings statements to be included in the subject report or portion
      thereof? [ ] Yes [x] No

      If so, attach an explanation of anticipated change, both narratively and
      quantitatively, and if appropriate, state the reasons why a reasonable
      estimate of the results cannot be made.

                      MICRO BIO-MEDICAL WASTE SYSTEMS, INC.
                  (Name of Registrant as Specified in Charter)

Has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.

Date March 29, 2006                             By:/s/ Charles Smith
                                                   ------------------
                                                   Charles Smith, CFO

      Instruction: The form may be signed by an executive officer of the
      registrant or by any other duly authorized representative. The name and
      title of the person signing the form shall be typed or printed beneath the
      signature. If the statement is signed on behalf of the registrant by an
      authorized representative (other than executive officer), evidence of the



      representative's authority to sign on behalf of the registrant shall be
      filed with the form.

                                    ATTENTION

      Intention misstatements or omissions of fact constitute Federal criminal
      violations. (See 18 U.S.C. 1001)